What if there were a place where every stratum of beauty and wellness, from core vitality to surface radiance, could be thoughtfully elevated in one extraordinary setting? Infused with playful luxury and anchored in cutting-edge science, EXO offers precisely this kind of transformative experience.
Located just a short drive from St. Louis in Edwardsville, Illinois, EXO is far more than a MedSpa. It's a comprehensive destination for health, beauty and longevity. Within its striking 20,000-square-foot facility, discerning guests discover an extensive menu of services designed to address virtually every facet of aesthetic and wellness needs. From rejuvenating facials, chemical peels and dermaplaning to advanced laser skin resurfacing, radiofrequency microneedling, laser hair removal, Botox, fillers and biostimulation, EXO seamlessly combines cutting-edge technology with an artful, personalized approach. The commitment to holistic well-being goes far deeper, offering IV therapy, hormone optimization, hair restoration, targeted pain management and the exceptional BodEvolv program, which is a bespoke strategy for sustainable weight management and enhanced longevity.
But EXO is also a place of true delight and sophisticated indulgence. After MedSpa treatments, one can retreat to the ground-floor nail bar, described aptly as a “sanctuary of artistry,” where nail care becomes not just grooming, but a powerful act of self-expression and holistic restoration. Treatments such as collagen wraps and red-light therapy go far beyond mere aesthetics, nurturing cellular health and a profound sense of renewal.
Top off visits with a handcrafted cocktail or savor an exquisite dish prepared by Michelin-starred chef Gianni Colucci.
Gina Gamblin, EXO’s founder, along with brand strategist Alex Petrou, emphasize that EXO was designed for clients who value the level of luxury typically found in New York or Los Angeles, now thoughtfully brought to the heart of the Midwest. “It’s a culture of life, wellness and longevity,” Alex shares. “A destination where you can truly step away from the minutiae of daily life and invest wholly in yourself.”
Gina elaborates that EXO is dedicated to creating sensual, sustaining experiences that are genuinely designed for long-term health and vitality.
“Clients are beginning to understand self-care not as indulgence, but as an essential priority.” Alex adds, “When we intentionally prioritize our own well-being, we become better, more present, more vibrant, for the people who depend on us. At EXO, there’s no guilt here. Come in your sweats, come as you are. This is your personal sanctuary.”
That welcoming philosophy extends gracefully to families as well. Select services are available for children, and with hours stretching until 10 p.m. most days, even the busiest clients can find time to prioritize their own care on their terms.
Under the expert medical direction of Dr. Chris Main, DO, each guest’s experience is carefully customized to maximize results and support sustainable wellness. Nowhere is this more evident than in EXO’s pioneering BodEvolv program. Through comprehensive body composition analysis, metabolic assessments, targeted lab panels and selected medications, including GLP-1/GIP, phentermine, and peptides, clients embark on highly individualized journeys toward weight management and extended vitality. Energy and metabolic function are further optimized with LipoB, B12 injections, and exceptional supplements, crafting a rigorous strategy that supports wellness from the inside out.
Complimentary skin consultations or comprehensive health assessments, complete with advanced labs and diagnostic testing, can be scheduled.
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